Large private managed-care HIV programme for employed people in Southern Africa which has over 280,000 adult and pediatric patients. Patients are treated by private medical practitioners. AfA contracts directly with companies or medical insurance companies to administer HIV care.

CIDRZ is the largest non-profit healthcare research organization in Zambia and has an extensive technical and support infrastructure to facilitate ongoing healthcare, research, and training activities. CIDRZ contributes data to IeDEA-SA from 77 clinics to which it provides support.

The Hannan Crusaid Treatment Centre at the Gugulethu Community Health Centre is a large ART service in Gugulethu, with more than 17,000 children, adolescents, and adults currently accessing care. Gugulethu is an urban suburb of Cape Town in the Western Cape of South Africa and was one of the first public sector ART programs in South Africa, providing care since 2002.

Harriet Shezi Paediatric ARV Clinic at Chris Hani Baragwanath Hospital in Soweto is one of the largest clinics of its kind in South Africa. It started in 2002 as a pediatric HIV ART initiation and HIV care site and has evolved into a tertiary level HIV clinic supporting all of Region D and Region G in Johannesburg. In 2020, the clinic has seen more than 10,000 children and adolescents and has initiated about 6,500 on ART.

The KwaZulu-Natal Research Institute for TB-HIV (K-RITH) and Africa Centre for Population Health have joined to form an exciting new interdisciplinary research institute, called the Africa Health Research Institute. The aim is to become a source of fundamental discoveries into the susceptibility, transmission and cure of HIV and TB and related diseases, seeking always to improve diagnosis, prevention and treatment.
The new organisation, the Africa Health Research Institute, is located at the heart of South Africa’s TB and HIV co-epidemic. It combines the renowned Africa Centre for Population Health’s detailed population data from over 100 000 participants, with the KwaZulu-Natal Research Institute for TB-HIV’s (K-RITH’s) basic science, experimental medicine and world-class laboratory facilities.

The Khayelitsha ART service, situated in the Western Cape Province, began in 2001 as one of the pioneering primary care ART programs in South Africa. By 2020, this urban cohort has enrolled nearly 60,000 patients on ART across 11 facilities within the Khayelitsha township. Today, the ART services are run by two local authorities (Provincial Department of Health and Metropolitan City Health directorate), which also run laboratory services, staff, M&E systems and procurement.

Kheth’Impilo AIDS Free Living is a nonprofit organization that has supported government Departments of Health with public health systems innovations, technical assistance, service delivery and research in five sub-Saharan African countries. Kheth’Impilo currently contributes data to IeDEA-SA from public health facilities in the Alfred Nzo, Chris Hani, and Oliver Tambo districts in the Eastern Cape province of South Africa. This province has an HIV prevalence amongst those aged 15-49 years of 20% and over 50,000 patients are currently receiving ART at these facilities.

Lighthouse Trust, a Public Trust and WHO-recognized Center of Excellence (COE) for integrated HIV prevention, treatment, care and support in Malawi, works in close collaboration with the MoH to operate four large integrated HIV testing, treatment and care clinics: Lighthouse at Kamuzu Central Hospital, Martin Preuss Center at Bwaila District Hospital in Lilongwe, Umodzi Family Clinic in Blantyre, and Tisungane Clinic in Zomba. Lighthouse currently has over 133,000 patients alive on ART in all the COEs and Lighthouse-supported health facilities.

The South African HIV Cancer Match (SAM) Study is the largest HIV-cancer linkage study globally, providing sufficient power to explore rare cancers, cancers in women living with HIV and specific sub-groups such as children, adolescents, and the elderly. The SAM Study has extensive geographic and population coverage for South Africa, with all population groups adequately represented. It also allows for comparisons by province and tracing interprovince transfers. The longitudinal nature of the data facilitates the follow-up of patients through the health care system.

Newlands Clinic runs an HIV treatment program in Harare, Zimbabwe -SA. Currently the clinic provides comprehensive care to over 6800 HIV infected patients. It is operated as a model private-public partnership with the Zimbabwe Ministry of Health and Child Care and Swiss Aids Care International.

RMMCH is the only hospital providing care specifically for women and children in Gauteng Province, and runs the second largest ARV clinic for the treatment of children infected with HIV in Gauteng province. The hospital also boasts one of the leading PMTCT programs, as well as a research unit conducting clinical and HIV-related trials with international and local collaboration. The public sector service provides ART and HIV-related care for approximately 1,500 children ranging in age from a few months to 18 years, plus a few young adults transitioning into the mainstream healthcare system. The clinic has rendered services to just under 5,000 HIV infected children.

The Red Cross War Memorial Children’s Hospital project is located within a tertiary referral hospital in Cape Town, South Africa. It is one of two tertiary referral centres in the Western Cape province, providing advanced care to sick children aged less than 15 years. Although over 2,000 children have been commenced on ART, the majority have been intentionally referred to their local community-based HIV clinics for ongoing care within the context of a decentralized model, with RCWMCH only retaining those children requiring specialist care.

SolidarMed Lesotho is active in rural Butha-Buthe and Mokhotlong, two of ten districts in Lesotho.. The SMART project aims to improve access to quality HIV and chronic disease services for the population of these districts. At district and national level, a solid collaboration has been established with the Ministry of Health, the District Health Management Teams and other stakeholders.

Solidarmed is active in the rural districts of Ancuabe and Chiure, which are situated in the Northern Province of Cabo Delgado, Mozambique. The SMART project aims to improve access to quality HIV and chronic disease services in the District. Recent achievements include the progressive decentralization of HIV services within the district by steadily increasing number of health centres offering HIV testing, counselling, and PMTCT services as well as ART.

The SMART project is active in the rural districts of Bikita and Zaka, which are situated in the province of Masvingo in Zimbabwe. The project aims to improve access to quality HIV and TB services for the population of the two districts. At district, provincial and national levels, a solid collaboration has been established with the Ministry of Health and the project works under the leadership of the Provincial Medical Director’s office.

The Health Economics and Epidemiology Research Office (HERO) of the Wits Health Consortium, University of the Witwatersrand, Johannesburg, South Africa, is a research unit founded in 2004 under the auspices of the Faculty of Health Sciences at the University of the Witwatersrand in Johannesburg. It is dedicated to understanding the economic and epidemiological consequences of the HIV/AIDS epidemic and the effectiveness, benefits, and costs of interventions. It undertakes applied economic and epidemiological analysis aimed at generating relevant, practical information for policy makers and program managers.

Tygerberg Hospital (TBH) is one of two tertiary care facilities situated in Cape Town, serving the population of the Western Cape Province. TBH provides tertiary healthcare to half of the Western Cape and secondary level healthcare to the area of the Cape Town metropole surrounding the hospital. The family clinic was established in 1997 as a service for children and adults infected with HIV and funded from external sources. The ART Clinic is responsible for the provision of ART in adults and children living in the vicinity of the hospital as well as managing complicated referrals.

In 2020, the province had an estimated 520,000 people living with HIV, approximately 50,000 patients with current TB diagnosed in the previous 12 months), and nearly 300,000 with previous TB. Within the Western Cape Government Department of Health jurisdiction are 479 facilities in 32 sub-districts and six districts (five rural districts and four sub-districts in metropolitan Cape Town). The following free services are offered: antenatal and PMTCT, ART, family planning, infectious diseases management including TB diagnosis and treatment, termination of pregnancies, legal services related to medical attention, oral (dental) health services (scholars and mobile clinics only), immunizations and primary health care services.