Prof. Egger has a long-standing interest in the clinical epidemiology of HIV, including HIV-related cancers and other co-morbidities, with over 20 years of experience in HIV observational cohort research. He was instrumental in establishing the Antiretroviral Therapy Cohort Collaboration (ART-CC) in the 2000s, and later the ART in Lower Income Countries (ART-LINC), to estimate prognosis of HIV-1 infected, treatment-naïve patients initiating combination ART. He is also involved in the large COHERE collaboration (Collaboration of Observational HIV Epidemiological Research in Europe) and the Swiss Tuberculosis Network. Together with colleagues from the London School of Tropical Medicine and Hygiene, Prof.Egger leads the mortality working group of the HIV Measurement, Surveillance & Evaluation Methods (MeSH).
Prof. Egger has served as co-Principal Investigator of IeDEA-SA since its inception in 2006. Under his leadership, IeDEA-SA project staff have served a key role in initiating and developing a joint collaboration between IeDEA global consortium and the WHO and UNAIDS. He has been Director of the Institute of Social and Preventive Medicine (ISPM) since 2002 and from January 2017, he will become the elected president of the Research Council of the Swiss National Science Foundation (SNSF).